Microtubule Depolymerization by Kinase Inhibitors: Unexpected Findings of Dual Inhibitors
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چکیده
منابع مشابه
Microtubule Depolymerization by Kinase Inhibitors: Unexpected Findings of Dual Inhibitors
Microtubule-targeting agents are widely used as clinical drugs in the treatment of cancer. However, some kinase inhibitors can also disrupt microtubule organization by directly binding to tubulin. These unexpected effects may result in a plethora of harmful events and/or a misinterpretation of the experimental results. Thus, further studies are needed to understand these dual inhibitors. In thi...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2017
ISSN: 1422-0067
DOI: 10.3390/ijms18122508